Comparison of plasma creatinine levels with the glomerular filtration rate showed a strong correlation sufficient to allow estimation of the GFR from the plasma creatinine levels.

estimated creatinine clearance in males =

= (94.3 / (serum creatinine in mg/dL)) - 1.8) mL/min per 1.73 meters-squared BSA


estimated creatinine clearance in females =

= (69.9 / (serum creatinine in mg/dL)) + 2.2) mL/min per 1.73 meters-squared BSA



• The adjustment for body surface area (BSA) is given on page 219 of Edwards and Whyte (1959).

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