Primary malignant tumors (usually adenocarcinoma) can rarely metastasize to the penis. A patient who develops a penile metastasis tends to have a dismal prognosis with a poor 1-year survival rate.
Primary sites that may metastasize to the penis include:
(1) colorectal adenocarcinoma
(2) bladder cancer
(3) lung adenocarcinoma
(4) cholangiocarcinoma
(5) prostate
(6) kidney
The history of cancer may be known, or the metastasis may be the first sign.
The patient may present with:
(1) a penile mass
(2) erectile dysfunction
(3) priaspism
(4) lower urinary tract symptoms
The diagnosis requires exclusion of:
(1) primary penile malignancy
(2) tuberculosis, syphilis, amebiasis or other infectious disease
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