MELD Scores of Chen et al Using eGFR

eGFR equations in mL per min per 1.73 square meter:

(1) abbreviated MDRD model (MDRD-4)

(2) MDRD model with 6 components (MDRD-6)

(3) CKD-EPI

Other parameters:

(4) serum total bilirubin in mg/dL, with minimum value 1

(5) INR, with minimum value 1

MELD using MDRD-4 =

= (8.82 * LN(INR)) + (4.07 * LN(serum total bilirubin)) - (5.13 * LN(eGFR)) + 30.57

MELD using MDRD-6 =

= (8.78 * LN(INR)) + (3.93 * LN(serum total bilirubin)) - (5.14 * LN(eGFR)) + 30.05

MELD using CKD-EPI=

= (8.80 * LN(INR)) + (4.01 * LN(serum total bilirubin)) - (5.37 * LN(eGFR)) + 31.93

Performance:

• The area under the ROC curve for the MDRD-6 equation is 0.91. This was slightly greater than the MELD score using serum creatinine.