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MELD-Cystatin Score of Maiwall et al for Predicting Acute Kidney Injury (AKI) in a Patient with Cirrhosis

Description

Maiwall et al reported a score for predicting acute kidney injury (AKI) in a patient with cirrhosis. This can help to identify a patient who may benefit from more aggressive management. The authors are from the Institute of Liver and Biliary Sciences and the All India Institute of Medical Sciences in India.


Patient selection: cirrhosis

 

Parameters:

(1) MELD score

(2) serum cystatin C in mg/L

 

MELD-Cystatin score =

= 10 * ((0.075 * MELD) + (1.679 * LN(cystatin C)))

 

where:

• The original equations used LOG without base specification. LN assumed.

• Serum cystatin C > 1.4 mg/L is associated with worse outcomes.

 

Interpretation:

• A cutoff value was not reported.

 

Performance:

• The area under the ROC curve is 0.84.


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