The Mayo risk score for primary sclerosing cholangitis (PSC) can be used to assess a patient's prognosis. A liver biopsy is required for calculating the score.
Parameters:
(1) age of patient in years
(2) serum bilirubin in mg/dL
(3) hemoglobin in g/dL
(4) stage on liver biopsy according to Ludwig et al (Contemp Issues Surg Pathol. 1986; 8: 193-213).
(5) presence or absence of inflammatory bowel disease
|
Parameter |
Finding |
Value |
|
serum bilirubin in mg/dL |
bilirubin < 10 |
bilirubin |
|
|
bilirubin >= 10 |
10 |
|
hemoglobin in g/dL |
hemoglobin < 12 |
hemoglobin |
|
|
hemoglobin >= 12 |
12 |
|
biopsy stage |
1 or 2 |
1 |
|
|
3 |
2 |
|
|
4 |
4 |
|
presence of inflammatory bowel disease |
no |
0 |
|
|
yes |
1 |
where:
• serum bilirubin value is the MIN(bilirubin,10)
• hemoglobin value is the MIN(hemoglobin,12)
risk score R =
= (0.06 * (age in years)) + (0.85 * (LN(bilirubin value))) - (4.39 * (LN(hemoglobin value))) + (0.51 * (biopsy value)) + (1.59 * (inflammatory bowel disease value))
Interpretation
|
R value |
Risk Group |
|
<= -5.14 |
low |
|
-5.13 to -3.26 |
intermediate |
|
>= -3.25 |
high |
Purpose: To use the Mayo risk score to predict prognosis in a patient with Primary Sclerosing Cholangitis (PSC).
Specialty: Gastroenterology, Immunology/Rheumatology
Objective: risk factors, other testing, severity, prognosis, stage
ICD-10: K83.0,
