Kiechle et al discussed the various factors affecting the upper limit for blood specimen volume during a given time period. The author is from Boca Biolistics Reference Laboratory.
Parameters:
(1) estimated blood volume in mL (from equations such as Nadler)
(2) time frame (per day or per month)
(3) percent of blood volume as upper limit
(4) patient healthy or sick
Sick
Healthy
per day
2.5%
3.0%
per month
5%
10%
maximum amount of blood that can be drawn for a given time period in mL =
= (total blood volume* (percent based patient health status and time period)
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