Markers of Debast et al for an Unfavorable Outcome for a Patient with Clostridium difficile Disease (European Markers of Clostridium difficile Disease Severity)
Debast et al reported markers associated with an unfavorable outcome for a patient with Clostridium difficile disease. The authors are from multiple institutions in Europe.
Patient selection: Clostridium difficile disease
Parameters:
(1) age in years
(2) white blood cell count per microliter
(3) serum creatinine in µmol/L
(4) serum albumin in g/L
(5) comorbidity
(6) ICU admission
Parameter
Finding
Points
age in years
<= 65 years
0
> 65 years
1
WBC count
<= 15,000 per µL
0
> 15,000 per µL
1
serum creatinine
< 133 µmol/L AND < 1.5 times premorbid level
0
>= 133 µmol/L
1
>= 1.5 times premorbid level
1
serum albumin
>= 30 g/L
0
< 30 g/L
1
comorbidity
none, mild or moderate
0
severe and/or immunodeficiency
1
ICU admission
no
0
yes
1
total score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• The higher the score the greater the risk for an unfavorable outcome.
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