Occasionally a patient infected with cytomegalovirus (CMV) may develop a marked lymphocytosis.
Clinical features:
(1) marked lymphocytosis which may persist for some time
(2) evidence of infection with CMV
(3) variable infectious mononucleosis-like syndrome
The proliferation should be polyclonal.
Differential diagnosis:
(1) acute leukemia
(2) other clonal lymphoproliferation
(3) drug reaction
Other infections associated with lymphocytosis:
(1) Epstein Barr virus (EBV)
(2) pertussis
(3) rubella
(4) mumps
(5) viral hepatitis
(6) chickenpox
(7) toxoplasmosis
(8) babesiosis
(9) cat-scratch disease (Bartonella henselae)
(10) HIV (CD8 T-cell lymphocytosis, diffuse infiltrative lymphocytosis syndrome)
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Specialty: Hematology Oncology, Infectious Diseases
