The mapping functions of Haldane and of Kosambi allow conversion between mapping units and recombination fractions used in genetic maps.
(1) Haldane's function does not allow for genetic interference
(2) Kosambi's function assumes genetic interference
map units (Haldane) in centiMorgans =
= (-0.5) * (LN(1 - (2 * (recombination fraction))))
recombination fraction =
= 0.5 * (1 - (EXP((-2) * (map units Haldane))))
• The unit of measurement for genetic maps is the centimorgan (cM).
map units (Kosambi) in centiMorgans =
= (0.25) * (LN((1 + (2 * (recombination fraction))) / (1 - (2 * (recombination fraction)))))
= 0.5 * (((EXP(4 * (map units Kosambi))) - 1) / ((EXP(4 * (map units Kosambi))) + 1))
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