Bagul and Siriwardena reported the Manchester criteria for staging chronic pancreatitis. The authors are from Manchester Royal Infirmary in Manchester, England.
Patient selection: chronic pancreatitis (CP)
Parameters:
(1) imaging evidence of chronic pancreatitis (endoscopic retrograde pancreatogram, MRI, CT)
(2) abdominal pain
(3) need for regular analgesia
(4) endocrine and exocrine function
(5) peri-pancreatic complications
Parameter
Mild CP
Moderate CP
End-Stage CP
imaging evidence
present
present
present
abdominal pain
yes
yes
NA
need for regular analgesia
no
weekly opiates (regular)
NA
endocrine and exocrine function
preserved
impaired
diabetes and/or steatorrhea
peri-pancreatic complications
none
none
biliary stricture, segmental portal hypertension, duodenal stenosis
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