Description

O'Shaughnessy et al proposed a management strategy for a woman based on cytologic findings on the fluid obtained at ductal lavage. The authors are from Baylor-Sammons Cancer Center in Dallas, Texas.


 

Patient selection: high risk for breast cancer after ductal lavage

 

If inadequate cellular material was obtained, then:

(1) an attempt is made to repeat the lavage at the next opportunity

(2) if the second exam is also inadequate AND if there was good fluid exchange (failure not due to duct perforation, failure to place the catheter properly) then perform followup in 1 to 3 years, else repeat.

Cytology

Action

normal, benign

Repeat ductal lavage in 1 to 3 years.

mildy atypia

Repeat ductal lavage in 0.5 to 1.0 years.

Consider preventive therapy unless contraindicated.

marked atypia or malignant

Repeat lavage to confirm findings.

Perform additional imaging studies.

Biopsy or explore if abnormality found.

Consider preventive therapy unless contraindicated.

 

where:

• Preventive therapy may include treatment with tamoxifen.

 


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