A patient with hemodialysis-associated pseudoporphyria (bullous dermatosis of hemodialysis) can be successfully managed.


Primary interventions:

(1) Change from low-flux to high-flux membrane hemodialysis.

(2) Administer oral N-acetylcysteine.


Adjunctive interventions:

(1) Avoid exposure to intense light sources.

(2) Discontinue or minimize use of drugs associated with pseudoporphyria.


Renal transplant would be expected to correct the disorder.


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