Patient selection: adult with bacterial meningitis in Malawi
Parameters:
(1) hemoglobin in g/dL from 2 to 20 g/dL
(2) Glasgow coma scale (GCS)
(3) pulse in beats per minute from 50 to 180
(4) LOG10 of white blood cells in the CSF per microliter
(5) CSF culture
points for hemoglobin =
= 111.111 - (5.5555 * (hemoglobin))
points for Glasgow coma scale =
= 122.5 - (8.1667 * (GCS))
points for pulse =
= (0.433846 * (pulse)) - 21.692
points for WBC count in CSF =
= 80.311 - (13.397 * LOG10(CSF WBC))
|
CSF Culture
|
Points
|
|
Strept pneumoniae
|
0
|
|
other
|
32
|
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 321.8
X =
= (0.031099 * (score)) - 4.4115
|
Score
|
Mortality Rate
|
|
< 31.1
|
< 3%
|
|
31.1 to 253.2
|
1/(1+EXP((-1) * X))
|
|
> 253.2
|
> 97%
|
