Malaria Score for Adults (MSA) of Mishra et al

Description

Mishra et al reported the Malaria Score for Adults (MSA) which is based on organ failures. This can help to identify a patient who may benefit from more aggressive management. The authors are from Ispat General Hospital and Sushilavati Government Women's College in Orissa, India, and the University of Maryland.

Patient selection: symptomatic adult with falciparum malaria

Parameters:

(1) severe anemia (hemoglobin < 5 g/dL)

(2) acute renal failure (serum creatinine > 3 mg/dL)

(3) respiratory distress syndrome

(4) cerebral malaria (unrousable coma)

Parameters	Findings	Points
severe anemia	absent	0
	present	1
acute renal failure	absent	0
	present	2
respiratory distress	absent	0
	present	3
cerebral malaria	absent	0
	present	4

total score =

= SUM(points for the 4 parameters)

Interpretation:

• minimum score: 0

• maximum score: 10

• The higher the score the greater the mortality.

Total Score	Mortality
0 to 2	2%
3 or 4	10%
5 or 6	40%
7 to 10	90%

Performance:

• The sensitivity was 90% and specificity 71%

• The positive predictive value was 94% when score >= 5.

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Malaria Score for Adults (MSA) of Mishra et al

Description

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