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Lymphocyte Cytotoxicity (LCT) Assay for Detecting Antibodies to HLA Antigens

Specialty:

Immunology/Rheumatology
Clinical Laboratory

Objective:

ICD-10:

Description:

Antibodies to HLA antigens can be detected using the lymphocyte cytotoxicity (LCT) assay. The patient's serum is tested against a panel of lymphocytes from different donors that have been characterized for HLA antigens. The same method can be used to identify a patient's HLA antigens, by testing the patient's cells against a panel of antibodies with known specificities.

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