Petri et al reported a score for lupus nephritis renal activity. This can help to monitor the severity of the renal disease. The authors are from multiple institutions participating as Systemic Lupus International Collaborating Clinics (SLICC).
Patient selection: SLE with lupus nephritis
Parameters:
(1) proteinuria (urine protein) in grams per day
(2) urine red blood cell count per high power field (hpf)
(3) urine white blood cell count per high power field (hpf)
Parameter
Finding
Points
urine protein
< 0.5 g/day
0
0.5 to 1.0 g/day
3
1.0 to 3.0 g/day
5
> 3.0 g/day
11
urine RBC
<= 10 per hpf
0
> 10 per hpf
3
urine WBC
<= 10 per hpf
0
> 10 per hpf
1
where:
• The urine counts are presumed to be performed on urine sediment (Development of case scenarios, page 1785).
• High power field is with a 40x objective.
total activity score =
= SUM(points for all 3 parameters)
Interpretations:
• minimum score: 0
• maximum score: 15
• The higher the score the greater the disease activity.
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