A patient with chronic obstructive pulmonary disease (COPD) or emphysema may be a candidate for lung transplant if certain poor prognostic factors are present.
Underlying disease:
(1) COPD
(2) emphysema secondary to alpha-1 antitrypsin deficiency
(3) emphysema secondary to other cause
Criteria for considering a patient for lung transplantation:
(1) functional Class III or IV NYHA
(2) postbronchodilator FEV1 < 25% of predicted (others: postbronchodilator FEV1 < 30% of predicted, FEV1 <= 20% of predicted)