Lung Cancer Prognostic Index of Alexander et al for Predicting Survival After the Diagnosis of Non-Small-Cell Lung Cancer (NSCLC): Modified Model (m-LCPI)
Alexander et al reported the Lung Cancer Prognostic Index (LCPI) for evaluating a patient with non-small-cell lung cancer (NSCLC). A modified version is available that is shorter in length. The authors are from multiple institutions in Australia.
Patient selection: non-small-cell lung cancer (NSCLC)
Difference from original LCPI: removal of ECOG PS and weight loss; change in stage scoring
Parameters:
(1) stage
(2) histologic type (adenocarcinoma, squamous cell, large cell, NOS)
(3) presence of a proven actionable mutation (EGFR, ALK, KRAS)
(4) smoking history
(5) respiratory comorbidity
(6) sex
(7) age group
Parameter
Finding
Points
Stage
I
0
II
2
IIIA
4
IIIB
6
IV
8
histologic type
NSCLC NOS
3
adeno, squamous, large cell
0
proven actionable mutation
no
3
yes
0
unknown
0
smoking history
never
0
previous
2
current
2
respiratory comorbidity
no
0
yes
2
sex
female
0
male
1
age group
<= 50 years
0
51 to 70 years
1
71 to 90 years
2
>= 91 years
3
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 22
Total Score
m-LCPI Group
<= 8
1
9 to 11
2
12 to 14
3
>= 15
4
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