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Lomotil (Diphenoxylate) Abuse and Dependence

Specialty:

Toxicology
Emergency Medicine
Critical Care

Objective:

ICD-10:

Description:

Lomotil is an anti-diarrheal product containing diphenoxylate and atropine. It is available as an over-the-counter combination product in many countries. Diphenoxylate is an opioid drug thought to be of low abuse potential, but abuse and dependence can occur. Diphenoxylate is an opioid of the phenylpiperidine subfamily. It is is classified as a schedule V controlled substance when mixed with atropine but schedule II if used alone.

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