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Liver Volume Ratios of Lazar et al for Predicting Outcome in a Fetus with an Isolated Left-Sided Congenital Diaphragmatic Hernia

Description

Lazar et al used the relative volume of liver hernitation to identify risk for a fetus with an isolated left-sided congenital diaphragmatic hernia. This can help to identify a neonate who may require more aggressive management including ECMO use.The authors are from Baylor College of Medicine in Houston.


 

Patient selection: isolated left-sided congenital diaphragmatic hernia

 

Method: ultrafast fetal MRI

 

Parameters:

(1) liver volume in the left hemithorax

(2) total liver volume

(3) total thoracic volume

 

percent liver herniation =

= (liver volume in left hemithorax) / (total liver volume) * 100%

 

liver to thoracic volume ratio =

= (liver volume in left hemithorax) / (total thoracic volume) * 100%

 

Interpretation:

• A percent liver herniation > 21% is associated with increased mortality and/or ECMO use.

• A liver to thoracic volume ratio > 14% is associated with increased mortality and/or ECMO use.

 


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Specialty

ICD-10