Patient selection: adult (>= 18 years) with cirrhosis listed for liver transplant
Parameters:
(1) gender-adjusted grip strength in kg
(3) number of chair stands per second (< 0.5 is impaired) based on a 30 second challenge
(4) balance time in seconds (< 30 seconds is impaired) based on standing for 10 seconds in 3 positions (feet together, semitandem, tandem)
adjusted grip strength = z score =
= ((observed value) - (average value for gender)) / (standard deviation for gender)
|
Gender
|
Mean
|
Standard Deviation
|
|
male
|
40
|
8.3
|
|
female
|
24
|
5.3
|
|
Parameter
|
Points
|
|
gender and grip strength
|
-0.330 * (adjusted strength)
|
|
chair stands
|
-2.529 * (stands per second)
|
|
balance time
|
-0.040 * (seconds)
|
liver frailty index =
= SUM(points for all of the parameters) + 6
Interpretation:
• minimum score: around 0
• maximum score: around 7
• The higher the score the greater the frailty.
• An index >= 4.5 is frail.
• An index <= 3 is robust.
