Leukocyte Alkaline Phosphatase Score


Leukocyte (neutrophil) alkaline phosphatase is a cytoplasmic enzyme present in myeloid cells from the metamyelocyte to mature segmented stages. The enzyme can be detected by conversion of a substrate to a colored product at an alkaline pH. A score based on staining intensity in 100 neutrophils can help in the diagnosis of some hematologic disorders.

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