Nagai et al reported a laboratory prediction score (LPS) for a terminally ill patient with a gastrointestinal malignancy. This can identify a patient with short life-expectancy. The authors are from Japanese Red Cross Aichi Medical Center in Nagoya.
Patient selection: terminally ill patient with a gastrointestinal carcinoma
Parameters:
(1) serum total bilirubin in mg/dL
(2) blood urea nitrogen (BUN) in mg/dL
(3) percent eosinophils in the differential count
(4) neutrophil-to-lymphocyte ratio (NLR)
(5) platelet count
Parameter
Finding
Points
serum total bilirubin
< 2.1 mg/dL
0
>= 2.1 mg/dL
1
serum BUN
< 28 mg/dL
0
>= 28 mg/dL
1
percent eosinophils
<= 0.5%
1
> 0.5%
0
NLR
< 9.2
0
>= 9.2
1
platelet count
<= 194,000 per µL
1
> 194,000 per µL
0
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
Score
Median Overall Survival
0 or 1
40 days
2 or 3
20 days
4 or 5
7 days
Score
14-Day Survival
0
100%
1
94%
2
87%
3
60%
4
32%
5
20%
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