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Laboratory Findings in non-ABO, non-D Alloantibody Hemolytic Disease of the Newborn (HDN)

Specialty:

Clinical Laboratory
Nephrology, Urology, Obstetrics & Gynecology, Pedatrics, Genetics
Nephrology, Urology, Obstetrics & Gynecology, Pedatrics, Genetics

Objective:

ICD-10:

Description:

The formation of alloantibodies by an antigen negative mother can result in hemolytic disease of the newborn (HDN) if the fetus is antigen-positive. If the mother forms IgG antibody then it can cross the placenta and attach to the fetus's red blood cells. If the alloantibody can reach the fetus for long enough and in high enough a titer then the patient may develop a hemolytic anemia which may lead to hydrops fetalis.

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