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Laboratory Findings in ABO-Incompatibility Hemolytic Disease of the Newborn (HDN)

Specialty:

Clinical Laboratory
Pedatrics
Obstetrics & Gynecology

Objective:

ICD-10:

Description:

ABO-incompatibility between mother and fetus can occasionally cause hemolytic disease of the newborn. Usually antibodies to ABO antigens are predominantly IgM and cannot cross the placenta. However, if the mother has high levels of IgG antibodies then these can cross the placenta and bind to fetal cells.

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