Clinical features:
(1) aphasia
(2) amnesia
(3) dementia
(4) seizures
(5) loss of anger and fear, with a placid demeanor and flattened affect
(6) visual agnosia (inability to recognize family or friends)
(7) constant exploration of the environment, often involving the placement of items into the mouth (hyperorality)
(8) hyperphagia, bulimia or other eating disorder
(9) hypersexuality
(10) delusions, echopraxia or other behavioral changes
Anatomic sites which may be affected:
(1) bilateral damage to the anterior and/or medial temporal lobe
(2) bilateral lesions of the amygdala (dorsomedial temporal pole anterior to the hippocampus)
(3) other lesions to the temporal lobes
Precipitating causes:
(1) head trauma
(2) encephalitis, especially after herpesvirus infection
(3) neurodegenerative disorders with dementia (Pick's disease, Alzheimer's disease, etc)
