Tornero et al reported the KLIC (or KLICC) score to predict failure of debridement as therapy of a prosthetic joint infection. The authors are from the University of Barcelona.
Patient selection: prosthetic joint infection following total hip or knee replacement
Outcome: failure of DAIR (debridement, antibiotics, implant retention)
Criteria for failure:
(1) unscheduled surgery within 60 days after initial debridement
(2) death from infection within 60 days
(3) prolonged suppressive antibiotic therapy
Parameters:
(1) chronic renal failure (K)
(2) liver failure (L)
(3) index surgery (I)
(4) cemented prosthesis (C)
(5) C-reactive protein (C) in mg/L
Parameter |
Finding |
Points |
chronic renal failure |
no |
0 |
|
yes |
2 |
liver failure |
no |
0 |
|
yes |
1.5 |
index surgery |
revision surgery |
1.5 |
|
prosthesis for femoral neck fracture |
1.5 |
|
other |
0 |
cemented prosthesis |
no |
0 |
|
yes |
2 |
CRP |
<= 115 mg/L |
0 |
|
> 115 mg/L |
2.5 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 9.5
Total Score |
Early Failure Rate DAIR |
<= 2 |
4.5% |
2.5 to 3.5 |
19.4% |
4 to 5 |
55% |
5.5 to 6.5 |
71% |
>= 7 |
100% |
Performance:
• The area under the ROC curve is 0.84.
Specialty: Infectious Diseases