Tornero et al reported the KLIC (or KLICC) score to predict failure of debridement as therapy of a prosthetic joint infection. The authors are from the University of Barcelona.
Patient selection: prosthetic joint infection following total hip or knee replacement
Outcome: failure of DAIR (debridement, antibiotics, implant retention)
Criteria for failure:
(1) unscheduled surgery within 60 days after initial debridement
(2) death from infection within 60 days
(3) prolonged suppressive antibiotic therapy
Parameters:
(1) chronic renal failure (K)
(2) liver failure (L)
(3) index surgery (I)
(4) cemented prosthesis (C)
(5) C-reactive protein (C) in mg/L
Parameter
Finding
Points
chronic renal failure
no
0
yes
2
liver failure
no
0
yes
1.5
index surgery
revision surgery
1.5
prosthesis for femoral neck fracture
1.5
other
0
cemented prosthesis
no
0
yes
2
CRP
<= 115 mg/L
0
> 115 mg/L
2.5
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 9.5
Total Score
Early Failure Rate DAIR
<= 2
4.5%
2.5 to 3.5
19.4%
4 to 5
55%
5.5 to 6.5
71%
>= 7
100%
Performance:
• The area under the ROC curve is 0.84.
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