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Description

Tornero et al reported the KLIC (or KLICC) score to predict failure of debridement as therapy of a prosthetic joint infection.  The authors are from the University of Barcelona.


Patient selection: prosthetic joint infection following total hip or knee replacement

 

Outcome: failure of DAIR (debridement, antibiotics, implant retention)

 

Criteria for failure:

(1) unscheduled surgery within 60 days after initial debridement

(2) death from infection within 60 days

(3) prolonged suppressive antibiotic therapy

 

Parameters:

(1) chronic renal failure (K)

(2) liver failure (L)

(3) index surgery (I)

(4) cemented prosthesis (C)

(5) C-reactive protein (C) in mg/L

 

Parameter

Finding

Points

chronic renal failure

no

0

 

yes

2

liver failure

no

0

 

yes

1.5

index surgery

revision surgery

1.5

 

prosthesis for femoral neck fracture

1.5

 

other

0

cemented prosthesis

no

0

 

yes

2

CRP

<= 115 mg/L

0

 

> 115 mg/L

2.5

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 9.5

 

Total Score

Early Failure Rate DAIR

<= 2

4.5%

2.5 to 3.5

19.4%

4 to 5

55%

5.5 to 6.5

71%

>= 7

100%

 

Performance:

• The area under the ROC curve is 0.84.


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