Kimmelstiel-Wilson syndrome describes a form of end-stage renal disease that can be seen in diabetics.
Clinical features of Kimmelstiel-Wilson syndrome include:
(1) diabetes mellitus
(3) severe proteinuria, sometimes with the nephrotic syndrome
(4) renal insufficiency
(5) variable diabetic retinopathy
A kidney biopsy typically shows nodular diabetic glomerulosclerosis. Mesangial nodules are called Kimmelstiel-Wilson lesions.
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Specialty: Nephrology, Clinical Laboratory, Endocrinology