A group of three findings may be a clue to the diagnoiss of Kearns-Sayre Syndrome.
Triad for Kearns-Sayre Syndrome:
(1) external ophthalmoplegia
(2) pigmentary retinopathy
(3) cardiac conduction defect, which may present with syncope
Other findings that may be detected:
(1) heart failure from ventricular dysfunction
(2) ptosis with compensatory wrinkling of the forehead
(3) endocrine disorder (diabetes, hypothyroidism, hypoparathyroidism, other)
(4) cerebellar ataxia
(5) elevated CSF protein (> 1 g/L)
