Kurosumi developed the J-score for reporting results of immunohistochemistry to demonstrate estrogen receptors in a woman with breast cancer. The author is from the Saitama Cancer Center in Japan.
Similarity to Allred score: Cells that stain are scored.
Difference from the Allred score: The intensity of staining is not scored.
Percent Tumor Cells Stained
J Score
Reporting Status
0%
0
negative
<= 1%
1
equivocal
1.01 to 9.99%
2
equivocal
>= 10%
3
positive
Interpretation:
• A woman with a J-score of 3 should respond to hormone-directed therapy.
• A woman with an equivocal J score may or may not respond to hormone-directed therapy. The number of patients falling into the equivocal group is small.
• A woman with a low J-score may respond to aromatase inhibitors.
Limitations:
• Reproducible results requires strict adherence to the testing and scoring guidelines.
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