Features of Isotretinoin Birth Defects | Medical Algorithm

Are you evaluating an infant born to a woman who took isotretinoin (Accutane) during the pregnancy?

Yes

Does the infant show?

• microtia and/or anotia?

Yes

• stenosis of the external ear canal?

Yes

• facial nerve paralysis?

Yes

• accessory parietal sutures?

Yes

• micrognathia?

Yes

• a depressed nasal bridge?

Yes

• ocular hypertelorism?

Yes

• cleft palate?

Yes

• hypoplastic left ventricle?

Yes

• interrupted aortic arch?

Yes

• ventricular and/or atrial septal defect?

Yes

• transposition of the great vessels?

Yes

• tetralogy of Fallot?

Yes

• truncus arteriosus?

Yes

• hydrocephalus?

Yes

• microcephaly?

Yes

• cerebellar hypoplasia or malformation?

Yes

• mental retardation?

Yes

• spina bifida?

Yes

• optic nerve blindness?

Yes

• retinal defects?

Yes

• microphthalmia?

Yes

• thymic defects?

Yes

• limb hypoplasia?

Yes

Evaluation

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Specialty

Objective

ICD-10

Features of Isotretinoin (Accutane) Embryopathy

Purpose: To evaluate an infant for malformations associated with isotretinoin (Accutane) embryopathy.