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BCG IRIS (Immune Reconstitution Inflammatory Syndrome) in HIV-Infected Child

Purpose:

To determine if an HIV-infected child immunized with BCG has developed an immune reconsistitution inflammatory syndrome (IRIS).

Specialty:

Infectious Diseases

Objective:

differential diagnosis and mimics, red flags, response to therapy, comorbid conditions

ICD-10:

A15, B20

Description:

Even though Bacille Calmette-Guerin (BCG) is contraindicated in patients with HIV infection, it still may be given to small children in developing countries with a high rate of tuberculosis. A vaccinated child may develop an immune reconstitution inflammatory syndrome (IRIS) following the initiation of highly active antiretroviral therapy (HAART).

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