El-Assal et al developed a score for predicting recurrence of a hepatocellular carcinoma following curative resection. These can help to identify a patient who may benefit from more aggressive management. The authors are Shimane Medical University in Izumo, Japan.
A curative resection was defined as removal of all grossly evident tumor at the time of surgery, with no evidence of tumor at 3 and 6 weeks after surgery on imaging studies.
Parameters:
(1) invasion of the portal vein
(2) invasion of the hepatic vein
(3) invasion of the serosa
(4) intrahepatic metastases
(5) tumor capsule and invasion of tumor capsule (if capsule present)
Parameter |
Finding |
Points |
invasion of portal vein |
absent |
0 |
|
present |
3 |
invasion of hepatic vein |
absent |
0 |
|
present |
1 |
invasion of serosa |
absent |
0 |
|
present |
1 |
intrahepatic metastasis |
absent |
0 |
|
present |
3 |
tumor capsule |
none |
1 |
|
present, not invaded by tumor |
0 |
|
present, invasded by tumor |
3 |
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 11
• The higher the score the more likely the tumor will recur and the shorter the survival.
Total Score |
Invasiveness |
8 Year Disease Free Survival |
0 or 1 |
low |
54% |
2 to 4 |
moderate |
10% |
5 to 11 |
high |
0% |
Specialty: Hematology Oncology, Surgery, general, Gastroenterology
ICD-10: ,