APACHE III is a further refinement to the APACHE (Acute Physiology, Age, Chronic Health Evaluation) system intended to provide more accurate predictions of hospital mortality risk for the critically-ill hospitalized adult.


The calculations required for the prediction are somewhat complex, involving the combination of the following into a risk equation:

(1) the APACHE III score, composed of several subscores for age, chronic health, physiologic, acid-base and neurologic status

(2) a value reflecting admission status

(3) a value reflecting the major disease category.


From the risk equation, the risk of hospital mortality is calculated.


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