Ghadri et al reported a score for distinguishing Takotsubo syndrome from acute coronary syndrome (ACS). The authros are from multiple institutions in Europe participating in the International Takotsubo Registry.
Parameters:
(1) sex
(2) emotional trigger
(3) physical trigger
(4) ST-segment depression in ECG
(5) psychiatric disorder
(6) neurologic disorder
(7) QTc prolongation
Parameter
Finding
Points
sex
male
0
female
25
emotional trigger
no
0
yes
24
physical trigger
no
0
yes
13
ST segment depression
absent (excluding aVR)
12
present
0
psychiatric disorder
absent
0
present
11
neurologic disorder
absent
0
present
9
QTc prolongation
absent
0
present
6
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 100
• A score >=40 had an 89% sensitivity and 91% specificity for Takotsubo Syndrome.
• A score <= 31 diagnosed 95% acute coronary syndrome.
X =
= (0.171 * (score)) - 7.63
probability of takotsubo syndrome =
= 1 / (1 EXP((-1) * X)))
To read more or access our algorithms and calculators, please log in or register.
