Pugashetti et al reported a screening tool for interstitial lung disease (ILD). This can help to reduce diagnostic delay and potentially improve outcomes. The authors are from the University of California at Davis, University of California at Los Angeles, Weill Cornell Medicine, and Centre Hospitalier de l'Universite de Montreal.
Parameters:
(1) age in years
(2) total lung capacity (TLC) in liters
(3) FEV1 in liters/second
(4) DLco in mL/mm Hg/min
(5) height in cm
(6) indication risk category (IRC) for performing pulmonary function tests (PFT)
Indication Risk Category
Point for Category
asthma
0
bronchiectasis
1
cardiac disease
0
COPD/emphysema
1
cough and/or dyspnea
1
ILD
3
lung nodule
0
malignancy
0
other
0
pulmonary hypertension
2
restrictive lung disease, lung crackles, abnormal imaging, and hyoxemia
1
rheumatologic disease
3
sarcoidosis
2
Parameter
Points
age in years
0.0544 * (age)
total lung capacity
- 0.7827 * (TLC)
FEV1
1.4567 * (FEV1)
DLco
-0.2336 * (DLco)
height
0.0694 * (height)
indication risk category
1.1645 * (IRC)
score =
= SUM(points for all of the parameters) - 3.9
Interpretation:
• The scores in the study ranged from 0 to 15.
• A score >= 8 indicates a positive ILD screen.
Performance:
• The area under the ROC curve is 0.91
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