D'Inca et al identified factors associated with nonadherence with drug therapy in patients with inflammatory bowel disease (IBD). Nonadherence with therapy may be associated with relapses and other complications. The authors are from the University of Padua in Italy.


Risk factors for nonadherence:

(1) age < 40 years

(2) forgetfulness

(3) disease in remission

(4) recent diagnosis of IBD

(5) full-time employment with a busy life

(6) multiple daily doses

(7) difficulty taking therapy at work or with activities


Factors associated with better compliance:

(1) oral therapy (vs topical therapy with enemas, foam or suppositories)

(2) good relationship with doctor; better communication


It is important to educate the patient so that s/he are aware of the importance of disease control even when asymptomatic. Therapy should be as convenient as possible.


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