Sun et al reported a simple prognostic score for patients with diffuse large B-cell lymphoma using inflammatory markers. This can help to identify a patient who may benefit from more aggressive management. The authors are from State Key Laboratory of Oncology in South China and Sun Yat-Sen University in Guangzhou.
Patient selection: diffuse large B-cell lymphoma (DLBCL)
Parameters:
(1) serum C-reactive protein (CRP) concentration in mg/L
(2) serum albumin concentration in g/L
(3) lymphocyte to monocyte ratio (LMR)
Parameter
Finding
Points
serum CRP
<= 8.6 mg/L
0
> 8.6 mg/L
1
serum albumin
>= 41.5 g/L
0
< 41.5 g/L
1
LMR
> 2.7
0
<= 2.7
1
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The higher the score the worse the prognosis.
Total Score
Risk Group
3-Year Overall Survival
0
ICPS0
96%
1
ICPS1
88%
2
ICPS2
76%
3
ICPS3
62%
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