A patient should be screened for hyperaldosteronism if certain clinical findings are present.
Patient selection: sustained hypertension (> 150/100 mm Hg on each of 3 readings taken on different days)
Indications to screen for primary hyperaldosteronism:
(1) hypokalemia (spontaneous or diuretic-induced)
(2) sleep apnea
(3) resistance to blood pressure medications (uncontrolled on 3 medications, controlled on 4 or more)
(4) mass in the adrenal gland (incidentaloma)
(5) family history of early onset hypertension and/or stroke (less than 40 years of age)
(6) first degree relative with primary hyperaldosteronism
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Specialty: Endocrinology, Clinical Laboratory
