Shohat and Halpern listed indications for evaluating a patient for Familial Mediterranean Fever (FMF). The authors are from Rabin Medical Center in Israel.
Reasons to suspect FMF in a patient:
(1) first-degree relative with FMF
(2) member of a high risk ethnic group (Armenian, Turk, Arab, Jew from North Africa, Iraq or Ashkenazi)
(3) recurrent episodes of fever with peritonitis, synovitis and/or pleuritis
(4) recurrent episodes of skin erythema resembling erysipelas
(5) history of laparotomy for acute abdomen with negative findings, especially if multiple
(6) amyloidosis of the AA type not explained by other causes
(7) positive response to continuous colchicine therapy
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