Indications of Ghannoum et al for Extracorporeal Therapy for Thallium Poisoning

Patient selection: thallium poisoning

Method of extracorporeal therapy:

(1) intermittent hemodialysis

(2) continuous renal replacement therapy (CRRT)

(3) intermittent hemoperfusion

Indications for extracorporeal therapy:

(1) thallium exposure is highly suspected

(2) serum thallium concentration > 1.0 mg/L (some recommend if > 0.4 mg/L)

Extracorporeal therapy should be started as soon as possible, preferably within 48 hours of the exposure.

Goal of therapy:

(1) serum thallium concentration < 0.1 mg/L for >= 72 hours (thallium absorption may be prolonged due to paralytic ileus)