Clay et al identified a number of indications for MDM2 FISH testing of a lipomatous tumor. The authors are from Emory University in Emory.
Location of MDM2: 12q15
Medical necessity: identify atypical lipomatous tumor/well-differentiated liposarcoma (ATL/WDL)
Indications for MDM2 testing:
(1) recurrent lipomatous tumor
(2) deep extremity lipomatous tumor AND > 10 cm in diameter AND age > 50 years
(3) equivocal atypia
(4) lipomatous tumor of retroperitoneum, pelvis or abdomen
(5) suspicious clinical and/or radiologic features (clinical concern)
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Specialty: Hematology Oncology, Surgery, general, Surgery, orthopedic
ICD-10: ,