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Indications for the Use of Diphenhydramine (Benadryl) in Allergic Transfusion Reactions

Description:

Some patients may develop urticaria and other allergic symptoms following blood product transfusion. Diphenhydramine (Benadryl, other brand names) is often given both to alleviate these symptoms and to prevent their occurrence. While relatively innocuous in most patients, diphenhydramine may be associated with significant side effects, especially in the elderly.

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