Measuring antibodies to herpes simplex virus (HSV) may be indicated in a number of clinical situations.
HSV antibodies to measure:
(1) Type 1 IgM
(2) Type 1 IgG
(3) Type 2 IgM
(4) Type 2 IgG
Indications for serologic testing:
(1) To distinguish primary from recurrent disease in a patient with positive viral testing (viral culture, PCR).
(2) To confirm a clinical diagnosis of HSV infection, especially when viral culture or PCR have been negative.
(3) To determine if a sexual partner of a patient with HSV is infected.
(4) To screen a patient with recurrent symptoms and negative urine cultures.
(5) As part of a workup for sexually transmitted disease (STD).
Additional situations to consider serologic testing for HSV:
(1) The patient is HIV positive.
(2) The patient is pregnant.
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Specialty: Infectious Diseases, Obstetrics & Gynecology, Urology, Otolaryngology, Clinical Laboratory
ICD-10: ,