Plasmaphereis may be helpful for carefully selected patients with systemic lupus erythematosus (SLE). Patients undergoing plasmapheresis receive immunosuppression, typically with corticosteroids and cyclophosphamide.
Indications for plasmapheresis - both of the following:
(1) disease resistant/refractory to immunosuppressive or alternative therapy
(2) severe, life-threatening disease with one or more of the following:
Other complications of SLE may occasionally benefit from plasmapheresis. These include conditions such as diffuse cutaneous vasculitis or the anti-Ro (SSA) syndrome prior to development of congenital complete heart block.
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