Most patients with poststreptococcal glomerulonephritis due not require a renal biopsy to make the diagnosis. A percutaneous renal biopsy should be considered if certain factors are present.


Reasons to consider performing a renal biopsy in a patient with poststreptococcal glomerulonephritis - one or more of the following:

(1) absence of antistreptococcal antibodies

(2) absence of hypocomplementemia

(3) more severe renal failure

(4) renal failure lasting more than 6 weeks

(5) duration of hypocomplementemia > 2 months

(6) proteinuria lasting > 6 months

(7) hematuria lasting > 12 months


The goal of the renal biopsy is to either confirm the diagnosis of poststreptococcal glomerulonephritis or to identify another condition misdiagnosed as poststreptococcal glomerulonephritis.


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