A patient with severe asthma may require respiratory support if there is evidence of respiratory failure.


Patient selection: hospitalized patient with severe anemia


Indications for respiratory support (intubation with mechanical ventilation):

(1) coma or worsening mental status

(2) apnea

(3) hemodynamic instability

(4) signs of exhaustion despite optimum bronchodilator therapy

(5) refractory hypoxemia with PaO2 < 60 mm Hg

(6) persistent hypercapnia with PaCO2 > 55 to 77 mm Hg

(7) increasing PaCO2 at > 5 mm Hg per hour


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