Antithrombin III levels should be measured when certain clinical findings are present.
Unexplained deep vein thrombosis or pulmonary embolus:
(1) personal history
(2) active disease
(3) family history
Presence of an underlying condition associated with acquired antithrombin III deficiency:
(1) DIC
(2) proteinuria
(3) cirrhosis
Possible resistance to heparin therapy:
(1) failure of aPTT or other monitoring test to prolong as expected for a given dosage regimen
(2) recurrent thrombotic event while on heparin
Situations increasing desirability of screening:
(1) preoperative
(2) possibly with oral contraceptive therapy
To read more or access our algorithms and calculators, please log in or register.
Specialty: Hematology Oncology, Clinical Laboratory
