Toxic:
(1) carbon monoxide poisoning
(2) severe cyanide poisoning
Infectious:
(1) Clostridial myonecrosis (gas gangrene)
(2) necrotizing soft tissue infections
(3) refractory osteomyelitis
(4) intracranial abscess
Trauma and environmental injury:
(1) acute traumatic ischemia, including crush injury and the compartment syndrome
(2) severe thermal burns
(3) decompression sickness
(4) air or gas embolism
(5) severe blood loss anemia
Radiation injury:
(1) radiation-induced osteonecrosis
(2) radiation-induced skin ulcerations
Skin ulcerations and wounds:
(1) problematic pressure, ischemic or diabetic skin ulcers
(2) skin flaps or skin grafts with marginal circulation
Hyperbaric oxygen therapy has been used experimentally or in extremis for other conditions.
