Description

Yamamoto-Furusho et al reported an index for describing the activity of ulcerative colitis. The authors are from Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran in Mexico City.


Patient selection: ulcerative colitis

 

Parameters:

(1) number of bloody bowel movements per day

(2) hemoglobin in g/dL

(3) serum high sensitivity CRP in mg/dL

(4) serum albumin in g/dL

(5) findings on endoscopy

(6) findings on histopathology

 

Parameter

Finding

Points

bloody bowel movements

none

0

 

2 or 3

1

 

4 to 6

2

 

> 6

3

hemoglobin

> 12 g/dL

0

 

10 to 12 g/dL

1

 

8 to 9.9 /dL

2

 

< 8 g/dL

3

serum CRP

<= 0.2 mg/dL

0

 

0.21 to 0.35 mg/dL

1

 

0.36 to 1.0 mg/dL

2

 

> 1.0 mg/dL

3

serum albumin

>= 3.5 g/dL

0

 

3.0 to 3.4 g/dL

1

 

2.5 to 2.9 g/dL

2

 

< 2.5 g/dL

3

endoscopic findings

normal mucosa

0

 

erythema, vascular pattern decreased, mild friability

1

 

marked erythema, absent vascular pattern, erosions, friable

2

 

ulceration, spontaneous bleeding

3

histopathology

normal

0

 

mild activity

1

 

moderate activity

2

 

severe activity

3

 

total score =

= SUM(points for all 6 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 16

 

Score

Activity

0 to 3

in remission

4 to 6

mild activity

7 to 12

moderate activity

13 to 18

severe activity

 


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