Yamamoto-Furusho et al reported an index for describing the activity of ulcerative colitis. The authors are from Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran in Mexico City.
Patient selection: ulcerative colitis
Parameters:
(1) number of bloody bowel movements per day
(2) hemoglobin in g/dL
(3) serum high sensitivity CRP in mg/dL
(4) serum albumin in g/dL
(5) findings on endoscopy
(6) findings on histopathology
Parameter |
Finding |
Points |
bloody bowel movements |
none |
0 |
|
2 or 3 |
1 |
|
4 to 6 |
2 |
|
> 6 |
3 |
hemoglobin |
> 12 g/dL |
0 |
|
10 to 12 g/dL |
1 |
|
8 to 9.9 /dL |
2 |
|
< 8 g/dL |
3 |
serum CRP |
<= 0.2 mg/dL |
0 |
|
0.21 to 0.35 mg/dL |
1 |
|
0.36 to 1.0 mg/dL |
2 |
|
> 1.0 mg/dL |
3 |
serum albumin |
>= 3.5 g/dL |
0 |
|
3.0 to 3.4 g/dL |
1 |
|
2.5 to 2.9 g/dL |
2 |
|
< 2.5 g/dL |
3 |
endoscopic findings |
normal mucosa |
0 |
|
erythema, vascular pattern decreased, mild friability |
1 |
|
marked erythema, absent vascular pattern, erosions, friable |
2 |
|
ulceration, spontaneous bleeding |
3 |
histopathology |
normal |
0 |
|
mild activity |
1 |
|
moderate activity |
2 |
|
severe activity |
3 |
total score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 16
Score |
Activity |
0 to 3 |
in remission |
4 to 6 |
mild activity |
7 to 12 |
moderate activity |
13 to 18 |
severe activity |
Specialty: Gastroenterology